THE DEPOSITION AND SUBSEQUENT COURSE OF PARTICULATE MATERIAL (MANGANESE DIOXIDE AND MANGANESE META-SILICATE) ADMINISTERED INTRAVENOUSLY TO CATS AND TO RABBITS.

1. Suspensions of manganese dioxide given intravenously to the cat are virtually eliminated from the body in 1 week (168 hours). 2.

THE FACTORS CONCERNED IN THE APPEARANCE OF NUCLEATED RED BLOOD CORPUSCLES IN THE PERIPHERAL BLOOD : II. INFLUENCE OF PROCEDURES DESIGNED TO INCREASE THE RATE OF BLOOD FLOW THROUGH THE BLOOD-FORMING ORGANS-HEMORRHAGE AND INFUSION.

1. Hemorrhage with immediate saline infusion causes the appearance in the peripheral blood of a slightly increased number of normoblasts provided normoblasts are already present in the blood stream. Marrow hyperplasia does not intensify this reaction and the cells found probably do not leave the marrow pulp but are in the blood stream at the time of the experiment.

THE FACTORS CONCERNED IN THE APPEARANCE OF NUCLEATED RED BLOOD CORPUSCLES IN THE PERIPHERAL BLOOD : I. INFLUENCE OF PROCEDURES DESIGNED TO INCREASE THE RATE OF BLOOD FLOW THROUGH THE BLOOD-FORMING ORGANS-EXERCISE AND NERVE SECTION.

1. Increase in circulatory rate caused by hard exercise has no power to dislocate nucleated red cells from the bone marrow either in normal, in anemic, in hyperplastic, or in anemic and hyperplastic animals. 2.