A pictorial view of the three-dimensional representation and comparative two-dimensional image orientation derived from computed tomography angiography in a dog with a patent ductus arteriosus.

Patent ductus arteriosus (PDA) occlusion is one of the more common cardiovascular procedures performed in dogs. Two-dimensional imaging has been the primary method of visualizing the PDA and is the basis of its morphologic description. Transesophageal echocardiographic imaging has further characterized the three-dimensional (3D) variation in ductal morphology and shape (circle, oval).

Comparative, multidimensional imaging of patent ductus arteriosus and a proposed update to the morphology classification system for dogs.

Background: Accurately assessing the morphology and shape of the patent ductus arteriosus (PDA) and obtaining measurements are important to avoid procedural complications.

Objectives: To characterize and compare PDA morphology, shape, and dimensions with angiography and echocardiography.

Animals: 25 client-owned dogs with echocardiographically confirmed PDA.

Real-time 3D transesophageal echocardiography-guided closure of a complicated patent ductus arteriosus in a dog.

Advanced imaging modalities are becoming more widely available in veterinary cardiology, including the use of transesophageal echocardiography (TEE) during occlusion of patent ductus arteriosus (PDA) in dogs. The dog in this report had a complex history of attempted ligation and a large PDA that initially precluded device placement thereby limiting the options for PDA closure. Following a second thoracotomy and partial ligation, the morphology of the PDA was altered and device occlusion was an option.

Simian T-lymphotropic Virus-associated lymphoma in 2 naturally infected baboons: T-cell clonal expansion and immune response during tumor development.

Two young female baboons naturally infected with simian T-lymphotropic virus type 1 (STLV1) were euthanized due to chronic respiratory disease that was unresponsive to treatment. Massive lymphocytic infiltration of the lung interstitium suggested a diagnosis of STLV-associated lymphoma. In each case, the diagnosis was confirmed through inverse PCR (IPCR) that detected monoclonally integrated STLV1 provirus in cellular DNA extracted from lymphoma tissue and peripheral blood cells (PBC).