Publications by authors named "K R Donegan"
Habits are the behavioral output of two brain systems. A stimulus-response (S-R) system that encourages us to efficiently repeat well-practiced actions in familiar settings, and a goal-directed system concerned with flexibility, prospection, and planning. Getting the balance between these systems right is crucial: an imbalance may leave people vulnerable to action slips, impulsive behaviors, and even compulsive behaviors.
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- The study aimed to evaluate the impact of the UK MHRA's March 2019 Risk Minimisation Measures (RMM) on the usage of fluoroquinolones using interrupted time series (ITS) methods.
- It analyzed monthly and quarterly fluoroquinolone usage data from various healthcare settings between 2012 and 2022, employing segmented regression and ARIMA models to assess changes across different age groups.
- Results showed significant reductions in fluoroquinolone usage after the RMM implementation across multiple databases, but some statistical issues such as heteroscedasticity and non-normality were observed in hospital-level data.
Article Synopsis
- Model-based planning helps prevent reliance on habits and is less effective in individuals with high compulsivity, although the impact is small and task-dependent.
- A new diamond-shooting smartphone game was designed to measure model-based planning in a home environment, assessing how different game structures affect measurement reliability and validity related to compulsivity.
- The study found that using fewer trials could effectively measure model-based planning, especially when tasks were less deterministic, suggesting the app is a viable tool for identifying compulsive behavior in the general population.
Purpose: There is increasing recognition of the importance of transparency and reproducibility in scientific research. This study aimed to quantify the extent to which programming code is publicly shared in pharmacoepidemiology, and to develop a set of recommendations on this topic.
Methods: We conducted a literature review identifying all studies published in Pharmacoepidemiology and Drug Safety (PDS) between 2017 and 2022.