Publications by authors named "K R Branson"
Genome-wide association studies (GWASs) have identified tens of thousands of disease associated variants and provided critical insights into developing effective treatments. However, limited sample sizes have hindered the discovery of variants for uncommon and rare diseases. Here, we introduce KGWAS, a novel geometric deep learning method that leverages a massive functional knowledge graph across variants and genes to improve detection power in small-cohort GWASs significantly.
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- Animals prioritize visual features based on their needs, but less is known about how they adjust their attention as goals change, particularly during social interactions.
- This study focuses on how female Drosophila (fruit flies) modify their visual processing when aggressive, identifying three specific neural circuit motifs that help these flies respond to visual cues related to aggression.
- The research finds that similar neural mechanisms are used in male Drosophila during courtship, highlighting a shared circuitry underlying different social behaviors in these flies.
Article Synopsis
- Robust data privacy regulations can limit the sharing of healthcare data, which is essential for gaining global insights and creating generalized clinical models.
- Federated learning (FL) offers a solution by enabling the training of global models using diverse datasets while maintaining patient privacy, but challenges arise from inconsistencies in electronic health records (EHRs).
- The paper presents a new FL framework that uses knowledge abstraction and filtering to manage these data discrepancies, allowing for effective global model training without needing manual data alignment or losing information.
Animals are often bombarded with visual information and must prioritize specific visual features based on their current needs. The neuronal circuits that detect and relay visual features have been well-studied. Yet, much less is known about how an animal adjusts its visual attention as its goals or environmental conditions change.
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