Publications by authors named "K R Abhilash"
Background: Pyrethroid insecticides are commonly used insecticides. This study was undertaken to characterize the clinical profile and outcome of deliberate self-harm (DSH) with type 1 and type 2 pyrethroids and identify factors associated with need for hospitalization.
Methods: This retrospective study was conducted in a tertiary care hospital in South India to study the clinical features, treatment, and outcome of patients with pyrethroid poisoning due to DSH.
Article Synopsis
- Orientia tsutsugamushi, the cause of scrub typhus, was successfully isolated from patients' blood cells at a healthcare center in Vellore, Southern India.
- Researchers cultured and tested samples using various methods over 30 days, ultimately confirming three positive isolates through qPCR and other staining techniques.
- Genotyping revealed the isolates belonged to TA763 and Gilliam genotypes, marking the first successful isolation of this pathogen in the region, with potential for further genomic study.
On-treatment decline in MELD score predicts one-month transplant-free survival in rodenticidal hepatotoxicity patients treated with low-volume plasma exchange.
Indian J Gastroenterol
December 2024
Article Synopsis
- Plasma exchange (PLEX) is shown to improve survival rates in patients with rodenticidal hepatotoxicity, but the factors that predict treatment success remain unclear.
- A study analyzed 200 patients over nearly a decade to identify predictors of survival, focusing on changes in MELD score, bilirubin levels, and INR after PLEX treatment.
- Results indicated that a significant decline in MELD score during treatment was the strongest independent predictor of one-month survival without liver transplantation.
EASIER trial (Erector-spinAe analgeSia for hepatopancreaticobiliary pain In the Emergency Room): a single-centre open-label cohort-based randomised controlled trial analysing the efficacy of the ultrasound-guided erector-spinae plane block compared with intravenous morphine in the treatment of acute hepatopancreaticobiliary pain in the emergency department.
Emerg Med J
September 2024
Background: Ultrasound-guided (USG) erector-spinae plane block (ESPB) may be better than intravenous opioids in treating acute hepatopancreaticobiliary (HPB) pain in the ED.
Methods: This open-label randomised controlled trial was conducted in the ED of a tertiary-care hospital between March and August 2023. All adult patients with severe HPB pain were recruited during times that a primary investigator was present.
Optimizing Surgical Management of Acute Invasive Fungal Sinusitis.
Turk Arch Otorhinolaryngol
December 2023
Objective: Early surgical debridement is vital for favorable outcomes in acute invasive fungal sinusitis (AIFS). Our study aimed to propose guidelines with tailored, conservative surgical procedures based on areas of involvement and evaluate their usefulness in avoiding repeated debridement.
Methods: This retrospective observational study was conducted on 150 AIFS patients operated on with the proposed surgical guidelines from May to June 2021 at a tertiary care hospital.