Ethanolic extract of Akhuni induces ROS-mediated apoptosis through ERK and AKT signalling pathways: Insights from metabolic profiling and molecular docking studies.

Akhuni, an ethnic food of northeast India, induces ROS-mediated apoptosis in cancer cells. This is the first report on the anticancer potential of Akhuni. Akhuni is a traditional fermented soybean product known for its umami taste and delicacy, commonly used in Northeast India's cuisine.

Differential Cytotoxic Effects of Cell-Free Supernatants of Emerging Pathogens and on Four Cell Lines Reveal Vero Cells as a Putative Candidate for Cytotoxicity Analysis.

and are recognized as emerging pathogens with zoonotic potential. Despite their increasing importance, there is a paucity of data on the cytotoxicity of these two pathogens. Therefore, in the present study, we investigated the cytotoxic potentials of the cell-free supernatants from 10 and 15 isolates for their cytotoxic effects on four different cell lines (CHO, Vero, HeLa, and MDCK).

Prooxidant and anti-inflammatory potential of fruit and its phytochemical characterisation by UHPLC-Q-Orbitrap HRMS.

Pro-oxidants play a crucial role in cancer by causing oxidative stress that leads to apoptosis. The present study demonstrates the prooxidant and anti-inflammatory potential of ethyl acetate and methanolic extracts of fruit. Oxidation of Trolox and NADH activity indicated the pro-oxidant capacity of the extracts.