Publications by authors named "K Piechura"
Behav Brain Res
October 2019
Article Synopsis
- Kissorphin (KSO) is a new peptide derived from kisspeptin-10 that has shown anti-opioid activity similar to neuropeptide FF (NPFF).
- Researchers tested KSO's effects on morphine's rewarding actions in rats using the conditioned place preference (CPP) paradigm, finding that KSO inhibited the acquisition, expression, and reinstatement of morphine-induced CPP.
- The strongest effects were at doses of 10 nmol for acquisition and reinstatement, while the actions of KSO were blocked by the NPFF receptor antagonist RF9, highlighting KSO's anti-opioid properties.
