Publications by authors named "K Phadke"

Atrial arrhythmias occur in 20-40% of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) and are associated with an increased risk of sustained ventricular arrhythmias and inappropriate implantable cardioverter-defibrillator shocks. The pathophysiology of atrial arrhythmias in ARVC remains unclear. Most cases of gene-positive ARVC are linked to pathogenic variants in the desmosomal gene plakophilin-2 (PKP2).

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  • Scientists studied the kinematic Sunyaev-Zel'dovich (kSZ) effect using data from two telescopes, the South Pole Telescope and Herschel-SPIRE, covering a large area in the sky.
  • They found a strong signal indicating that there is a trispectrum, which is a kind of pattern in the data, but it had contributions from other sources too, like cosmic microwave background lensing and foregrounds.
  • By analyzing the data, they couldn't find just the kSZ signal alone, but they set limits on how long the reionization period lasted in the early universe, which helps us understand its history better.
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A myriad of coronaviruses cause diseases from a common cold to severe lung infections and pneumonia. SARS-CoV-2 was discovered to be the etiologic agent of the Coronavirus pandemic and many laboratory techniques were examined for virus culture and basic and applied research. Understanding the replication kinetics and characterizing the effect the virus has on different cell lines is crucial for developing studies.

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While first generation SARS-CoV-2 vaccines were effective in slowing the spread and severity of disease during the COVID-19 pandemic, there is a need for vaccines capable of inducing durable and broad immunity against emerging variants of concern. Nanoparticle-based vaccines (i.e.

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  • The study investigates glottal dynamics in vocal fold disorders (leukoplakia, laryngitis, papilloma) using visualization technologies like PVG and GVG to improve diagnosis and classification.
  • The research employs high-speed video endoscopy and various imaging techniques to analyze the vibratory patterns of affected vocal folds, revealing distinct differences in their behavior.
  • Ultimately, the findings suggest that these advanced visualization methods provide crucial insights into vocal fold dynamics, supporting better understanding and assessment of voice disorders compared to traditional methods.
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