Publications by authors named "K Patrick"

Objective: Functional MRI (fMRI) helps with the identification of eloquent cortex to assist with function preservation in patients who undergo epilepsy surgery. Language and memory tasks can even be used effectively in clinically involved pediatric patients. Most pediatric studies report on English speaking-only cohorts from English-dominant countries, yet languages other than English (LOEs) are increasingly prevalent in countries such as the US.

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Objective: Prior work indicates that discrete emotions are linked to performance across multiple domains of cognitive function and thus have the potential to impact cognitive profiles in neuropsychological assessment. However, reported presence and magnitude of the relationships between emotion and cognitive test performance are inconsistent. Variable findings in this regard could be due to failure to consider motivations associated with expressed emotion.

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Article Synopsis
  • Treosulfan is an important treatment in allogeneic haematopoietic stem cell transplantation (allo-HSCT) for children, offering lower toxicity than traditional drugs.
  • Researchers studied the effects of treosulfan on 83 pediatric patients to see how it impacts survival, graft failure, and graft-versus-host disease.
  • The results showed no significant correlation between treosulfan exposure and clinical outcomes or toxicity, indicating that standardized dosing is effective for pediatric allo-HSCT.
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Acute promyelocytic leukaemia (APL), defined by the t(15;17)(q24;q21) translocation, accounts for 5%-10% of paediatric acute myeloid leukaemia cases. All-trans retinoic acid (ATRA) and arsenic trioxide (ATO) are key treatments, though ATO access varies. We evaluated treatment, complications and survival in 50 UK paediatric APL patients diagnosed between 2014 and 2021.

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Background: Motion Tape (MT) is a low-profile, disposable, self-adhesive wearable sensor that measures skin strain. Preliminary studies have validated MT for measuring lower back movement. However, further analysis is needed to determine if MT can be used to measure lower back muscle engagement.

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