Hyperbilirubinemia in Neonates with Blood Group Incompatibilities - a bane or a boon for the management.

Objectives: Neonatal hyperbilirubinemia, or newborn jaundice, is a common condition caused by high bilirubin levels. Blood group incompatibility between mother and baby is a major cause. This study examined the link between different blood group incompatibilities and their management in newborns with jaundice.

β-actin function in platelets and red blood cells can be performed by γ-actin and is therefore independent of actin isoform protein sequence.

Actin is an essential component of the cytoskeleton in every eukaryotic cell. Cytoplasmic β-and γ-actin are over 99% identical to each other at the protein level, but are encoded by different genes and play distinct roles in vivo. Blood cells, especially red blood cells (RBC), contain almost exclusively β-actin, and it has been generally assumed that this bias is dictated by unique suitability of β-actin for RBC cytoskeleton function due to its specific amino acid sequence.

Dehydroascorbic acid quantification in human plasma: Simultaneous direct measurement of the ascorbic acid/dehydroascorbic acid couple by UPLC/MS-MS.

Ascorbic acid (AA, vitamin C) and dehydroascorbic acid (DHA) constitute a biological couple. No technique can accurately, independently, and simultaneously quantify both members of the couple in animal and human samples, thereby constraining advances in physiology and pathophysiology. Here we describe a new UPLC/MS/MS method to measure both compounds directly and independently in human plasma.

p of alcohols dictates their reactivity with reduced uranium-substituted thiomolybdate clusters.

The uranium-substituted thiomolybdate cluster, (Cp*3Mo3S4)UCp*, has been demonstrated as a model for water reduction by single uranium atoms supported on a molybdenum sulfide surface (U@MoS). In this study, the scope of O-H bond activation is expanded through the investigation of the reactivity of various alcohols with differing p values for the -OH proton. The reaction of (Cp*3Mo3S4)UCp* with stoichiometric amounts of methanol, phenol, 2,6-dichlorophenol, and nonafluoro--butyl alcohol affords the corresponding mono-alkoxide species, (Cp*3Mo3S4)Cp*U(OR), a uranium-metalloligand cooperative activation of the O-H bond.