Publications by authors named "K Padmanabhan"

Article Synopsis
  • Nasal packing is a common procedure done after intranasal surgeries to prevent complications like bleeding and infections.
  • This study compared the effectiveness of Merocel nasal packing with Glove finger nasal packing after surgeries such as Septoplasty and Polypectomy.
  • Results showed no significant differences in outcomes, but patients with Glove finger packs experienced slightly faster mucociliary clearance, indicating both methods are effective.
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Article Synopsis
  • - Bardet-Biedl syndrome (BBS) is a rare genetic disorder that affects multiple systems in the body and presents unique difficulties, particularly in ear, nose, and throat (ENT) care for affected children.
  • - Two sibling cases are discussed: the older child faced complex surgical challenges due to obesity and anatomical issues, while the younger sibling had initial relief from surgery but later experienced recurring health issues related to adenoids, needing long-term monitoring.
  • - The report highlights the importance of teamwork among medical professionals in managing the intricate symptoms of BBS and calls for ongoing research to improve treatment strategies for similar cases in the future.
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In the early olfactory system, adult-neurogenesis, a process of neuronal replacement results in the continuous reorganization of synaptic connections and network architecture throughout the animal's life. This poses a critical challenge: How does the olfactory system maintain stable representations of odors and therefore allow for stable sensory perceptions amidst this ongoing circuit instability? Utilizing a detailed spiking network model of early olfactory circuits, we uncovered dual roles for adult-neurogenesis: one that both supports representational stability to faithfully encode odor information and also one that facilitates plasticity to allow for learning and adaptation. In the main olfactory bulb, adult-neurogenesis affects neural codes in individual mitral and tufted cells but preserves odor representations at the neuronal population level.

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Objective: The aim of this study is to evaluate the presence of laryngopharyngeal reflux in patients with voice disorders thereby aiding in the early management and improving the quality of life.

Study Design: Cross Sectional study.

Methods: This cross sectional study was carried out in a tertiary care hospital, patients with history of voice change for more than 3 weeks were included, and divided into 4 groups depending upon the level of voice use.

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Article Synopsis
  • - Human brain organoid models are valuable for researching brain development and function due to their ability to mimic human genetics and facilitate lab manipulation.
  • - There are ongoing concerns about the accuracy and reliability of these models, which need to be addressed to maximize their potential in science and medicine.
  • - The article reviews current techniques for analyzing these organoids, discusses existing challenges, and offers suggestions for improving consistency and precision in future research.
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