Publications by authors named "K P Steel"
The role of the opponent's head in perception of kick target location in martial arts.
Front Sports Act Living
December 2024
Athletes in Martial Arts must anticipate the target of their opponent's kick or strike to avoid contact. Findings suggest that features, e.g.
View Article and Find Full Text PDFRescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
Proc Natl Acad Sci U S A
December 2024
Variants in the gene cause Norrie disease, a severe dual-sensory disorder characterized by congenital blindness due to disrupted retinal vascular development and progressive hearing loss accompanied by sensory hair cell death. encodes the secreted signaling molecule norrin. The role of norrin in the cochlea is incompletely understood.
View Article and Find Full Text PDFArticle Synopsis
- Progressive hearing loss often has a genetic basis, with specific mutations like those in the microRNA miR-96 linked to hearing impairments in both humans and mice.
- This study examines two mouse models with different human mutations in miR-96, utilizing auditory tests and microscopy to analyze impacts on hearing and hair cell structure.
- Results show that while both mutations cause deafness in homozygous mice, heterozygous effects vary significantly, revealing potential therapeutic targets that could delay hearing loss progression in affected mice.
Stress CMR Perfusion Imaging in the Medicare-Eligible Population: Insights From the SPINS Study.
JACC Cardiovasc Imaging
January 2025
Article Synopsis
- - Patients aged 65 and older have a higher risk of cardiovascular (CV) events, and this study aimed to evaluate the effectiveness of stress cardiac magnetic resonance (CMR) for predicting these events in this age group across multiple centers in the U.S.
- - The research involved 1,780 seniors, finding that those with inducible ischemia or late gadolinium enhancement (LGE) showed significantly higher rates of serious CV events over nearly 5 years, while those without these conditions had a low event rate.
- - The study concluded that both inducible ischemia and LGE are strong predictors of primary and secondary CV outcomes, indicating that CMR can be a valuable tool for risk assessment in older patients.
Rheumatoid arthritis (RA) is an immune-mediated, chronic inflammatory condition. With modern therapeutics and evidence-based management strategies, achieving sustained remission is increasingly common. To prevent complications associated with prolonged use of immunosuppressants, drug tapering or withdrawal is recommended.
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