Effect of a neurostimulator on postnatal neurogenesis in rodent olfactory bulbs.

The aim of the study was to reveal the effect of neurostimulation with the TKPRPGP neuropeptide on the expression intensity of Doublecortin and Nestin in the olfactory bulb of white Wistar rats using immunohistochemical and computer analysis methods. An isolated assessment of early progenitor differentiation by the density of nestin-positive structures showed that stimulation from birth to 14 days preserves the level of nestin expression, preventing its decrease. When the administration of the neuropeptide is stopped, the expression of nestin decreases sharply, starting from the central zones of the bulb, and after three weeks it is no longer present.

Perioperative complications of pediatric otorhinolaryngological operations.

Background: The identification of risk factors for the development of perioperative complications is one of the most important problems of pediatric anesthesiology.

Purpose: To identify risk factors for the development of perioperative complications in children undergoing ambulatory surgical interventions on ENT organs.

Methods: Total of 141 patients were examined at the age from 7 to 17 years.