The QIBA Profile for Dynamic Susceptibility Contrast MRI Quantitative Imaging Biomarkers for Assessing Gliomas.

The dynamic susceptibility contrast (DSC) MRI measures of relative cerebral blood volume (rCBV) play a central role in monitoring therapeutic response and disease progression in patients with gliomas. Previous investigations have demonstrated promise of using rCBV in classifying tumor grade, elucidating tumor viability after therapy, and differentiating pseudoprogression and pseudoresponse. However, the quantification and reproducibility of rCBV measurements across patients, devices, and software remain a critical barrier to routine or clinical trial use of longitudinal DSC MRI in patients with gliomas.

All-cancer incidence and mortality in Pakistanis, Bangladeshis, and their descendants in England and Wales.

Background: This paper identifies differences in all-cancer incidence and mortality between Pakistani-born (PB), Bangladeshi-born (BB), their descendants, and the White British (WB) in England and Wales. Pakistanis and Bangladeshis are the most marginalised and disadvantaged groups in England and Wales yet, are found to have low cancer mortality and low all-cause mortality. Previous studies though have not looked at generational differences, applied individual-level data nor separated Pakistanis and Bangladeshis from each other and other Asian groups.

Paramagnetic salt and agarose recipes for phantoms with desired T1 and T2 values for low-field MRI.

Tissue-mimicking reference phantoms are indispensable for the development and optimization of magnetic resonance (MR) measurement sequences. Phantoms have greatest utility when they mimic the MR signals arising from tissue physiology; however, many of the properties underlying these signals, including tissue relaxation characteristics, can vary as a function of magnetic field strength. There has been renewed interest in magnetic resonance imaging (MRI) at field strengths less than 1 T, and phantoms developed for higher field strengths may not be physiologically relevant at these lower fields.

Intergenerational transmission of fertility in Great Britain: A parity-specific investigation using the 1970 British Cohort Study.

Studies in low-fertility settings have consistently found positive relationships between parents' and children's fertility timing and family sizes, and these persist after accounting for socio-demographic factors. We explore intergenerational transmission of fertility in Great Britain, where socio-economic inequalities are larger and could play a greater role in explaining intergenerational continuities than in other settings. Using the 1970 British Cohort Study, a long-running longitudinal data set, we estimate parity-specific discrete-time event-history models to investigate the role of mother's family size and age at first birth in birth transitions.