Publications by authors named "K P Exarchos"

Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous progressive lung condition characterized by long-term respiratory symptoms and airflow limitation. Appropriate bronchodilation is the cornerstone of COPD treatment, leading to better health status as well as benefits in prognosis and mortality.

Methods: In the current open, noninterventional, observational study, 716 patients diagnosed with COPD of variable severity were administered a fixed-dose combination (FDC) of fluticasone propionate and salmeterol (500 + 50 mcg) through the Elpenhaler® device.

View Article and Find Full Text PDF

Key Clinical Message: There is no consensus regarding the therapeutic approach of breast neuroendocrine carcinomas (NECs). As most NECs are hormone receptor positive and HER-2 negative, we suggest that endocrine-based strategies may play a leading role. Here, we report a new treatment strategy by incorporating CDK4/6 inhibitors in the therapeutic armamentarium.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine whether an educational video about airway collapsibility during sleep would improve the acceptance of CPAP treatment in patients with severe obstructive sleep apnea.
  • A total of 145 patients were analyzed, with one group receiving standard care and the other group watching the video before their treatment.
  • Results showed that 80% of patients who watched the video accepted CPAP therapy, compared to 57% in the standard care group, highlighting the video's positive impact on CPAP acceptance.
View Article and Find Full Text PDF

Background: Echocardiographic markers of right ventricular dysfunction or pressure overload (RV) have been used in risk assessment of patients with acute pulmonary embolism (APE). Nevertheless, the role of echocardiography in these patients is incompletely determined. We evaluated the right ventricular function using 'non-conventional' markers of RV in patients with APE.

View Article and Find Full Text PDF