Acrodermatitis Enteropathica in a Child in Bahrain: A Case Report and Literature Review.

Acrodermatitis enteropathica (AE) is a rare autosomal recessive disorder caused by a mutation in the zinc transporter gene, leading to impaired zinc absorption. A triad of periorificial dermatitis, alopecia, and diarrhea is the characteristic clinical presentation, although symptoms may vary with age. This disease typically manifests during infancy, particularly during the weaning process.

Genetically Confirmed Wilson Disease: A Retrospective Cohort Study From Bahrain.

Introduction Wilson disease (WD) is a rare inherited autosomal recessive disorder caused by a mutation in the gene. This mutation affects copper metabolism, leading to the accumulation of copper in the liver, brain, cornea, and other tissues. If not treated, WD can lead to significant morbidities.

High blood pressure in the emergency department as an opportunistic screening tool for detection of hypertension.

Hypertension is the most preventable cause of morbidity and mortality, but many individuals are underdiagnosed and lack treatment control. High blood pressure (BP) in the emergency department (ED) is commonly observed, but mostly used for short-term evaluation. We aimed to study the usefulness of high BP in the ED as a screening tool for undiagnosed hypertension.

Antiproliferative Impact of Linagliptin on the Cervical Cancer Cell Line.

Objective: This study aimed to assess linagliptin's inhibitory effects on the proliferation of cervical cancer cell lines and investigate its potential for targeting human heat shock protein 90.

Methods: Linagliptin's cytotoxicity was assessed on a cervical cancer cell line (Hela cancer cell line) at two different incubation periods, 24 and 72 hours. The molecular docking between linagliptin and the receptor protein human Hsp 90 (PDB code: 5XRE) was performed using the Biovia Discovery Studio and AutoDock tool software.