Incidence, outcomes, and risk factors of postlaparoscopic subcutaneous emphysema: a historical cohort study.

Purpose: Subcutaneous emphysema is a common complication of laparoscopic surgery. We aimed to determine the incidence, outcomes, and risk factors of postlaparoscopic subcutaneous emphysema.

Methods: We conducted a single-centre historical cohort study of adult patients who underwent laparoscopic surgery at Kagoshima University Hospital between 1 April 2018 and 31 March 2021.

Effect of Residual Pain After Posterior Fusion Surgery for Lumbar Degenerative Disorders on Health-Related Quality of Life: A Two-Year Follow-Up Using Patient-Reported Outcome Measures.

Study Design: This is a prospective cohort study.

Purpose: The present study aimed to investigate the effects of residual pain after fusion surgery for lumbar degenerative diseases on quality of life (QOL).

Overview Of Literature: Residual symptoms after spinal surgery often restrict patients' activities of daily living and reduce their QOL.

Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride.

A liver cyst is hepatic fluid-filled cavities often detected in clinical surveillances such as a health examination. Although the liver cyst is usually asymptomatic and observed without any therapeutic intervention, it can be symptomatic and needs treatment due to its enlargement, hemorrhage, and infection. A 74-year-old woman presented with upper abdominal pain and a huge liver cyst in the left lobe.

Facile End-Functionalization of Poly(Quinolylene-2,3-Methylene) Using the Terminal Palladium Complex: Thiocarbonylation through Formation of an Acyl Palladium Complex at the Polymer Terminal.

The end-functionalization of poly(quinolylene-2,3-methylene)s (PQM) via thiocarbonylation is successfully achieved by forming an acyl palladium complex. The terminal palladium complex of the PQMs synthesized by living cyclocopolymerization of o-allenylaryl isocyanide is quantitatively converted to a tractable acyl palladium complex through the carbon monoxide insertion into a palladium-carbon bond. The resulting acyl palladium complex exhibits high reactivity toward thiols, thereby enabling the introduction of various substituents at the ω-chain end of PQM by selectively converting them to thioester groups.

Synthesis of novel entecavir analogues having 4'-cyano-6''-fluoromethylenecyclopentene skeletons as an aglycone moiety as highly potent and long-acting anti-hepatitis B virus agent.

Encouraged by our recent findings that 4'-cyano-deoxyguanosine (2), entecavir analogues 4 and 5 are highly potent anti-hepatitis B virus (HBV) agents, we designed and synthesized 6 having a hybridized structure of 4 and 5. The chiral quaternary carbon portion at the 4'-position, which is substituted by cyano- and 5'-hydroxymethyl groups, was stereospecifically constructed by radical-mediated 5- mode cyclization of 10. The introduction of the fluorine atom into the 6''-position was achieved by radical-mediated stannylation of sulfide ()-11 and subsequent electrophilic fluorination of ()-12.