Publications by authors named "K Ohki"
Article Synopsis
- Biological neural networks, especially in the visual cortex of different species, process information through both spontaneous and stimulus-evoked activities, but how they handle internal noise vs. sensory signals is debated.
- In mouse primary visual cortex (V1), spontaneous and stimulus-evoked activities reveal dissimilar patterns, aiding in the separation of sensory information from noise, while higher similarity is observed in carnivores and primates.
- The study found that in marmosets, while V1 shows similar spontaneous and stimulus-evoked activity, higher visual areas exhibit an increasing orthogonalization of these patterns, suggesting a broader principle of cortical computation across species.
Purpose: The JCCG ALL-B12 clinical trial aimed to evaluate the effectiveness of unvalidated treatment phases for pediatric ALL and develop a safety-focused treatment framework.
Patients And Methods: Patients age 1-19 years with newly diagnosed B-ALL were enrolled in this study. These patients were stratified into standard-risk (SR), intermediate-risk (IR), and high-risk (HR) groups.
Objective Patients undergoing maintenance dialysis are at a higher risk of morbidity and mortality due to severe coronavirus disease 2019 (COVID-19) than the general population. However, longitudinal data regarding this subpopulation of patients are lacking. We therefore examined the prognosis of patients with COVID-19 undergoing maintenance dialysis between 2020 and 2023.
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- Genetically encoded fluorescent sensors are being enhanced to assess cortical activity in non-human primates, allowing for detailed measurements of brain dynamics.* -
- The Automated Robotic Virus injection System (ARViS) was developed to facilitate the precise delivery of biosensors across different cortical areas, utilizing image recognition to avoid blood vessels and enabling precise micropipette insertion.* -
- ARViS demonstrated its effectiveness by successfully injecting biosensors into 266 sites in a marmoset's frontoparietal cortex and enabling advanced imaging techniques to observe cortical activity.*