Publications by authors named "K Ogihara"

Article Synopsis
  • A 50-year-old woman was successfully diagnosed with idiopathic cerebrospinal fluid rhinorrhea using contrast-enhanced fluid-attenuated inversion recovery (FLAIR) imaging techniques.
  • Pre- and postcontrast FLAIR subtraction images revealed a protrusion in the right olfactory cleft canal, demonstrating the effectiveness of this imaging method alongside traditional CT and MR cisternography.
  • The confirmed diagnosis led to an endoscopic nasal surgery to repair the fistula, resulting in a positive clinical outcome.
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Background: Aplastic or twig-like middle cerebral artery (Ap/T-MCA) is a rare vascular anomaly that can cause hemorrhagic and ischemic stroke. Ap/T-MCA can induce aneurysms due to the fragility of the vessel wall, consequently leading to subarachnoid hemorrhage. Herein, we report a case of Ap/T-MCA with subarachnoid hemorrhage without an aneurysm.

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Diclofenac, a non-steroidal anti-inflammatory drug, reportedly targets mitochondria and induces nephrotoxicity via reactive oxygen species. However, there are few detailed reports of pathological analyses of mitochondria and the factors that cause acute kidney injury (AKI) as a result of nephrotoxicity. In this study, we investigated mitochondrial damage in the proximal tubule in AKI mice at 6, 12, and 24 h after administration of diclofenac.

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Article Synopsis
  • Mast cells produce cytokines and chemokines that are important in disease processes, and they contain high levels of the ganglioside GM3, which is essential for their function.
  • In a study, mast cells lacking GM3 synthase (GM3S) exhibited changes that made them overly reactive to stimuli, leading to increased inflammation without affecting their growth.
  • The absence of GM3S resulted in decreased membrane integrity and heightened skin allergic reactions, while restoring GM3 levels improved membrane stability and helped reduce excessive signaling linked to allergic responses.
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A 78-year-old man underwent a tracheostomy after embolization for a dural arteriovenous fistula. Seventy days after tracheostomy, arterial bleeding appeared through the tracheal stoma. The bleeding stopped spontaneously.

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