Publications by authors named "K O Eyong"
Article Synopsis
- The study investigates the clinical and socio-developmental characteristics of children with autism spectrum disorder (ASD) in a Nigerian tertiary hospital, addressing the lack of data in sub-Saharan Africa.
- It analyzed medical records from six years, identifying a prevalence of 1.6% among 1806 children with neurological disorders and highlighting that the average age for diagnosis was around 3.8 years.
- The findings revealed that the majority of diagnosed children were male, with comorbid conditions such as hyperactivity in over half of the cases and a small percentage having siblings with autism.
Background: Demyelinating disorders of the central nervous system (CNS) are rare disorders characterized by inflammation and the selective destruction of CNS myelin. The incidence of this disorder is increasing in developed countries. Nigerian studies on the pediatric population on the subject are very scarce.
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- The study examines acute hemiplegia in children, which is a brain response due to various causes after birth, aiming to identify its reasons and outcomes at the University of Calabar Teaching Hospital in Nigeria.
- Over five years, 25 children were reviewed; common findings included prolonged seizures, speech defects, and causes like viral encephalitis and sickle cell anemia.
- The results showed that while some children recovered fully, a majority experienced ongoing weakness, and a significant number were lost to follow-up, highlighting the need for better infection control and genetic counseling.
Background: Cerebral visual impairment (CVI), including perceptual visual dysfunction (PVD), is common in children with cerebral palsy (CP). Inventories of questions relating to practical aspects of visual perception in everyday life, in particular the closed-ended Insight Questions Inventory (IQI), can be used to assess CVI/PVD. Studies linking responses to the inventory with specific visual support strategies, aimed at modifying the child's environment and/or behaviour to minimize the impact of the CVI/PVD, have been piloted.
View Article and Find Full Text PDFFractionation of the ethyl acetate-soluble extract of the roots of Leplaea mayombensis afforded two new 3,4-seco-lanostane-type triterpenoids, leplaeric acids A and B (1, 2), the new lanostane-type triterpenoid leplaeric acid C (3), and six known natural products (5-10). Derivatization of the main constituent, 1, afforded the dimethyl ester 4, the monoamide 11, and diamide 12 for SAR studies. The structures of these compounds were established through spectroscopic methods, and a single-crystal X-ray diffraction analysis was used to confirm the relative configuration of compound 1.
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