Publications by authors named "K O Chua"
Article Synopsis
- Previous studies indicate a link between larger opioid prescriptions after surgery and the risk of new persistent opioid use (NPOU), but the connection between NPOU and actual postoperative opioid usage was unclear.
- This study analyzed data from over 36,000 patients who underwent surgery and were opioid naïve prior to their procedures, discovering that 1.3% developed NPOU, with higher opioid consumption in the first 30 days after discharge correlating to an increased risk of NPOU.
- Results suggest that each additional opioid pill taken in the post-surgery period raises the likelihood of developing NPOU, highlighting the critical role of careful opioid prescribing in preventing long-term opioid dependence.
is a multidrug-resistant bacterium that has emerged as a significant nosocomial pathogen globally and renowned for its ability to acquire antimicrobial resistance (AMR) genes. However, understanding of its resistance mechanisms to certain drug classes remains limited. This study focused on four bacterial strains (AB863, AB889, AB930, and AB960) exhibiting carbapenem resistance.
View Article and Find Full Text PDFAims And Method: A collaborative evaluation of remote consultations in mental health services was undertaken by mental health service providers, experts by experience, academic institutions and a Health Innovation Network in south London, UK. 'Learning healthcare systems' thinking was applied. Workstream 1 reviewed international published evidence; workstream 2 synthesised findings from three health provider surveys of the perceptions and experiences of staff, patients and carers; and workstream 3 comprised an electronic survey on local projects.
View Article and Find Full Text PDFObjective: Bariatric surgery effectively treats non-alcoholic fatty liver disease (NAFLD). The glutamate-serine-glycine (GSG) index has emerged as a non-invasive diagnostic marker for NAFLD, but its ability to monitor treatment response remains unclear. This study investigates the GSG index's ability to monitor NAFLD's response to bariatric surgery.
View Article and Find Full Text PDFBackground: We evaluated the feasibility, safety, and efficacy of a 2D-planar robot for minimally supervised home-based upper-limb therapy for post-stroke hemiparesis.
Methods: The H-Man, end effector robot, combined with web-based software application for remote tele-monitoring were evaluated at homes of participants. Inclusion criteria were: strokes > 28 days, Fugl-Meyer Motor Assessment (FMA) > 10-60/66, presence of a carer and absence of medical contraindications.