Publications by authors named "K Nose"
Introduction: Postoperative pneumonia may develop in infants after cardiac surgery; however, only a few reports are available on perioperative oral bacteria in infants. This study aimed to examine preoperative and postoperative salivary bacterial counts in infants undergoing cardiac surgery.
Materials And Methods: The number of bacteria in the saliva of 105 infants (average age: 20 months) who underwent surgery for congenital heart disease was determined by culturing before and after surgery.
Article Synopsis
- Glioblastoma stem cells (GSCs) contribute to the aggressive nature of glioblastoma by making the tumor resistant to therapies, and high levels of γ-Glutamylcyclotransferase (GGCT) are linked to this resistance.
- Inhibition of GGCT reduces GSC proliferation, and its expression is regulated by the protein c-Jun, which is influenced by the NRas protein.
- GGCT knockdown not only hampers GSC growth but also disrupts the Delta-Notch signaling pathway by lowering Notch1 levels, suggesting GGCT is a promising target for new glioblastoma treatments.
Background/aim: Glioblastoma is the most frequent type of adult-onset malignant brain tumor and has a very poor prognosis. Glioblastoma stem cells have been shown to be one of the mechanisms by which glioblastoma acquires therapy resistance. Therefore, there is a need to establish novel therapeutic strategies useful for inhibiting this cell population.
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- A study compared inside stent (IS) and conventional stent (CS) for preoperative biliary drainage in patients with localized perihilar cholangiocarcinoma (LPHC) using data from 56 patients.
- Results showed that the IS group had significantly fewer instances of recurrent biliary obstruction (RBO), longer time to RBO, and needed fewer stent replacements compared to the CS group.
- Additionally, patients with IS experienced shorter hospital stays and lower overall costs preoperatively and postoperatively, indicating potential benefits for both patients and the healthcare system.
A 54-year-old woman presented with an elevated esophageal lesion. Computed tomography (CT) and magnetic resonance imaging revealed a mass in the pancreatic head. Endoscopic ultrasound (EUS) showed a well-defined, round, hypoechoic mass, which was considered lymph node enlargement.
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