Publications by authors named "K Niiya"
Article Synopsis
- The study explored the connection between immunoglobulin A (IgA) levels and chronic liver disease in 478 patients at Nagasaki Harbor Medical Center, highlighting that higher IgA levels were found in patients with more severe conditions, such as Child-Pugh classification B and C and alcoholic liver disease.
- Analysis revealed that factors like high IgG levels, diabetes, and certain liver disease types contribute to elevated IgA levels, suggesting that elevated IgA might indicate increased liver disease severity.
- Results also showed a significant association between IgA levels and visceral fat, particularly in women, reinforcing the role of IgA as a potential marker for liver disease severity amidst rising cases of steatotic liver disease.
Thrombocytopenia, anasarca, fever, renal dysfunction, and organomegaly (TAFRO) syndrome is an inflammatory disorder with an unclear pathogenesis. We herein report a case of TAFRO syndrome in remission in a patient who experienced recurrent intracranial bleeding despite a normal platelet count and coagulation system. A further investigation suggested the presence of anti-glycoprotein VI (GPVI) autoantibodies in the plasma, which induced platelet dysfunction and bleeding tendency.
View Article and Find Full Text PDFWe present the case of a patient with pyelonephritis secondary to urinary tract obstruction caused by uterine prolapse. An 80-year-old woman with uterine prolapse (pelvic organ prolapse stage 4) was treated with a pessary at an outside hospital due to her high perioperative risk. However, the pessary prolapsed.
View Article and Find Full Text PDFIntroduction: We report the case of a patient who developed a severe pulmonary embolus postoperatively despite perioperative venous thromboembolism (VTE) prophylaxis as prescribed.
Presentation Of Case: A 50-year-old female patient underwent a robotic total hysterectomy for uterine fibroids. Her perioperative VTE risk was assessed as moderate, and compression and intermittent air compression stockings were used postoperatively until the morning following the surgery.
Trisomy X conferring moderate hemophilia A by extremely skewed X-chromosome inactivation.
Res Pract Thromb Haemost
October 2023
Background: Hemophilia carriers occasionally present with bleeding tendency due to skewed inactivation of normal carrying X chromosome.
Key Clinical Question: Can extreme skewing of X-chromosome inactivation (XCI) with trisomy X cause low factor (F) VIII activity and bleeding in a hemophilia carrier?.
Clinical Approach: A young female with low FVIII activity (2 IU/dL), who presented with history of frequent bleeding and variant, NP_000123.