Publications by authors named "K Nandheeswari"
Article Synopsis
- The gut microbiome plays a crucial role in male reproductive health and infertility, acting as a system that interacts with the endocrine and immune systems.
- Recent research on the gut-testis axis (GTA) suggests a connection between gut health and male reproduction, but some studies remain controversial.
- Various factors, including diet and pollutants, can either disrupt or support gut microbiota, impacting hormone activities in reproduction and highlighting the need for further exploration of the GTA for potential therapies.
Germ cells are highly conserved in the gonads, nurtured to either develop into a gamete or self-renew into a stem cell reserve. Preserving the germ cell pool and protecting the reproductive organs is essential for maintaining an individual's fertility. Several factors, including a sedentary lifestyle, pollutants, hormonal disruption, drugs, and a disease condition, have been shown to impair normal reproductive function.
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- Thyroid problems are common among women, especially those trying to conceive, and arsenic exposure has been linked to thyroid and ovarian issues, although their connection hasn’t been directly studied.
- The experiment involved female mice drinking varying concentrations of sodium arsenite for 30 days, revealing that arsenic reduced thyroid hormone levels and altered ovarian follicle count while indicating signs of hypothyroidism.
- The results suggest that arsenic disrupts thyroid function and ovarian development, potentially leading to fertility issues due to hormonal imbalances and impaired folliculogenesis.