Publications by authors named "K Nakatani"

Tissue flossing involves wrapping a rubber band around a muscle group for a few minutes while performing joint motion, enhancing ankle joint torque and range of motion. As limited ankle dorsiflexion range of motion and plantar flexion muscle weakness are risk factors for sports injury, assessing the therapeutic effects of tissue flossing is important. This study aimed to evaluate the immediate effects of calf tissue flossing on enhancing ankle joint torque and dorsiflexion range of motion.

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Article Synopsis
  • Abnormalities in spermatogenesis can lead to male infertility, highlighting the importance of testicular somatic cells in this process.
  • In a study using mice with a specific gene deletion, researchers found that the absence of normal spermatogenesis caused increased Leydig cell numbers and interstitial space in the testis.
  • The increase in Leydig cells correlated with higher testosterone production and signs of cellular aging, suggesting they play a role in supporting germ cell development during spermatogenesis.
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Background/aim: Nab-paclitaxel is used to treat patients with pancreatic cancer. However, it frequently induces peripheral neuropathy. Notably, pharmacokinetic factors may be associated with neuropathic symptoms as the onset depends on the cumulative dose.

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Myotonic dystrophy type 1 (DM1) is caused by the aberrant expansion of CTG repeats within the DMPK gene. This study investigated the potential binding of "X-linker-Y" type molecules to the CTG/CTG motif present in CTG repeats, using heterocyclic units X and Y capable of forming complementary hydrogen bonds with nucleobases. Among the tested molecules, the heterodimer of 2-amino-1,8-naphthyridine (X) and 3-aminoisoquinoline (Y) showed significant binding to the CTG/CTG motif.

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