Publications by authors named "K Nakamori"

Oral bacteria cause tooth caries and periodontal disease. Much research is being conducted to prevent both major oral diseases by rendering dental materials' antimicrobial potential. However, such antimicrobial materials are regarded as 'combination' products and face high hurdles for regulatory approval.

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Obesity is a worldwide health problem with a rapidly rising incidence. In organ transplantation, increasing numbers of patients with obesity accumulate on waiting lists and undergo surgery. Obesity is in general conceptualized as a chronic inflammatory disease, potentially impacting alloimmune response and graft function.

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Both age and biological sex affect transplantation outcomes. We have recently shown in a large volume clinical analysis utilizing the SRTR data that graft survival is inferior in young female kidney transplant recipients. In this multi-factorial analysis, older female recipients presented with a trend towards improved transplant outcomes compared to both young female recipients and male recipients of any age.

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Background: Living kidney transplant donors are classified as stage 3 chronic kidney disease after kidney donation. For this reason, we provide daily lifestyle guidance, such as blood pressure and weight management before surgery, and dietary counseling focused on salt restriction. We emphasize providing lifestyle guidance after kidney donation.

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Article Synopsis
  • - Bladder cancer (BC) patients can experience shrinkage due to radiation-induced fibrosis, and specific microRNAs (miRNAs) are linked to this injury and overall survival.
  • - In a study of three Japanese BC patients, certain miRNAs (such as hsa-miR-130a and hsa-miR-200c) were highly expressed in those with fibrotic bladder shrinkage compared to patients with intact bladder function.
  • - Analysis of 409 BC patients revealed that high expression of specific miRNAs correlated with significantly longer median survival, indicating a potential role for these miRNAs in predicting patient outcomes and targeting profibrotic cytokines.
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