Publications by authors named "K Naidu"
The lung tumor microenvironment (TME) or stroma is a dynamic space of numerous cells and their released molecules. This complicated web regulates tumor progression and resistance to different modalities. Lung cancer cells in conjunction with their stroma liberate a wide range of factors that dampen antitumor attacks by innate immunity cells like natural killer (NK) cells and also adaptive responses by effector T cells.
View Article and Find Full Text PDFEarly detection and management of cardiovascular diseases (CVDs) are crucial for patient survival and long-term health. CVD biomarkers such as cardiac Troponin-I (cTnI), N-terminal pro-brain natriuretic peptide (NT-proBNP), creatine kinase MB (CK-MB), Galectin-3 (Gal-3), etc are released into the circulation following heart muscle injury, ie, acute myocardial infarction (AMI). Biosensor technology including the use of nanoparticles can be designed to target specific biomarkers associated with CVD, enabling early detection and more rapid intervention to decrease morbidity and mortality.
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- Sleep deprivation has significant negative effects on both physical and mental health, disrupting the gut-brain axis and leading to imbalances in gut microbiota.
- This imbalance, known as dysbiosis, can worsen neurological disorders such as depression, anxiety, and cognitive decline through various mechanisms like increased neuroinflammation and compromised gut barriers.
- There is growing interest in therapeutic approaches like probiotics, dietary changes, and personalized interventions to restore gut health and alleviate sleep-related neurological issues, highlighting the need for further research in this area.
The rising presence of xylazine in Philadelphia's fentanyl supply has led to various upper-extremity complications in individuals who inject drugs. Sociogeographic trends predict that our current local phenomenon will spread nationally. We aim to discuss the drug's impact on clinical presentation and patient care via a cohort of five patients with upper-extremity wounds related to drug use.
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