Publications by authors named "K Nagesh"
Article Synopsis
- Surfactant therapy has proven highly effective for both preterm and term infants, especially those less than 28 weeks gestation, reducing their vulnerability and improving treatment outcomes.
- A subgroup analysis shows that using less invasive surfactant administration techniques (LISA/MIST) significantly lowers the need for mechanical ventilation by 28% and decreases the incidence of bronchopulmonary dysplasia (BPD) by 30% compared to traditional methods like intubation-surfactant-extubation (INSURE).
- The review emphasizes the need for personalized treatment approaches based on individual patient data, while no significant difference in mortality rates was found between the different surfactant administration methods.
A green and efficient process for the synthesis of cenobamate has been accomplished in 70% yield and >99% ee through the bio-reduction of β-ketotetrazole using Daucus carota whole plant cells. The corresponding β-hydroxytetrazole was isolated in 60% yield and >98% ee. This is the first report on the biocatalytic reduction of β-ketotetrazole using plant enzymes derived from D.
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- - The study aimed to create a mathematical formula to predict the optimal depth for spinal needle insertion based on neonates' gestation age and weight.
- - Researchers examined 127 neonates, using ultrasound to measure spinal canal depth, and found that both weight and post-menstrual age positively influenced spinal dimensions.
- - A strong correlation was identified between weight and spinal canal depth, leading to the formula MSCD (cm) = 0.2 × weight in kg + 0.45, which could help improve needle placement accuracy and reduce the risk of trauma during lumbar punctures.
Aim: The present study was conducted to validate cardiac output (CO) and cardiac index (CI) obtained from electrical cardiometry (EC) ICON with transthoracic echocardiography (TTE) in postoperative pediatric cardiac surgical patients.
Materials And Methods: A prospective observational study was conducted in 25 pediatric patients with age < 10 years who underwent elective cardiac surgery.
Data Analysis: BlandAltman plot was constructed for interchangeability and Polar plot was constructed to know trending ability.
Evidence-Based Consensus Recommendations for Skin Care in Healthy, Full-Term Neonates in India.
Pediatric Health Med Ther
August 2023
Purpose: Neonatal skin care practices guided by personal experience and preferences might be substantially different across different hospital settings. The aim of this consensus recommendation is to provide clinical practice guidance to healthcare practitioners on evidence-based neonatal skin care practices from delivery-to-discharge, in hospital settings.
Patients And Methods: A Scientific Advisory Board meeting on "Evidence-based Neonatal Skin Care Practices and Protocols" was held in December 2020 with an expert panel comprising neonatologists, pediatricians, obstetricians and gynecologists and pediatric dermatologist.