Publications by authors named "K Nagakura"
Background: Low-dose (LD) oral food challenge (OFC) with heated cow's milk (CM; 3 mL) effectively prevents CM elimination in children with CM allergy (CMA). We investigated the long-term prognoses after an LD-OFC for CMA.
Methods: Children with immediate CMA symptoms after consuming <25 mL of CM within 2 years of a baseline LD-OFC were retrospectively analyzed.
Background: The clinical importance of sensitization to 6 (Ara h 6) in Japanese children remains unelucidated. We aimed to quantitatively evaluate the clinical importance of sensitization to Ara h 6 in managing peanut allergy in Japanese children.
Methods: We retrospectively analyzed the data of children with or without symptoms induced by an oral food challenge or home dosing of up to 3 g of peanuts.
Article Synopsis
- The study investigates the effectiveness of recombinant Gad c 1 (rGad c 1) in diagnosing allergies to cod and horse mackerel, considering its potential as a major allergen marker for fish allergy in children.
- In this retrospective study involving 45 children with possible cod allergies and 38 with horse mackerel allergies, researchers analyzed both cod-specific and rGad c 1-specific immunoglobulin levels through oral food challenges (OFCs).
- Findings reveal that while rGad c 1 is a more reliable marker for diagnosing cod allergy compared to regular cod-specific antibodies, it is less effective for diagnosing horse mackerel allergy, indicating that further research is needed to fully understand rGad c
Food allergies are an increasing global problem and societal issue. In addition to the potential for severe allergic reactions from accidental ingestion, food allergies impose a significant burden on the quality of life, nutrition, cost of living, and social activities of both those afflicted and their caregivers. Strict avoidance of allergens and use of emergency medications to treat allergic reactions are the traditional management and treatment strategies; however, significant progress has been made in recent years toward better treatment of food allergies.
View Article and Find Full Text PDFBackground: Sublingual immunotherapy (SLIT) for perennial allergic rhinitis (AR) has not been extensively studied in preschoolers. We investigated the efficacy and safety of house dust mite (HDM) SLIT-tablet for children aged 1-4 years.
Methods: Children aged 1-4 years with AR were divided into SLIT (n = 22) and control (n = 12) groups based on their guardians' preferences.