Remote sensing of ice albedo using harmonized Landsat and Sentinel 2 datasets: validation.

Albedo plays a key role in regulating the absorption of solar radiation within ice surfaces and hence strongly regulates the production of meltwater. A combination of Landsat and Sentinel 2 data provides the longest continuous medium resolution (10-30 m) earth surface observatory records. An albedo product (harmonized satellite albedo, hereafter HSA) has already been developed and validated for the Greenland Ice Sheet (GrIS), using harmonized Landsat 4-8 and Sentinel 2 datasets.

Engineered vascular grafts lend unique insight to pathophysiology of aortic aneurysms.

Yang et al. generate tissue engineered blood vessels from hiPSC-derived smooth muscle cells harboring a mutation found in Loeys-Dietz syndrome. In vitro and in vivo data from these vessels provide new insight into the molecular physiology of aortic aneurysms and may create a paradigm for understanding a suite of vascular diseases.

Emerging effects of temperature on human cognition, affect, and behaviour.

Human body core temperature is tightly regulated within approximately 37 °C. Global near surface temperature has increased by over 1.2 °C between 1850 and 2020.

Revealing four decades of snow cover dynamics in the Hindu Kush Himalaya.

Knowledge about the distribution and dynamics of seasonal snow cover (SSC) is of high importance for climate studies, hydrology or hazards assessment. SSC varies considerably across the Hindu Kush Himalaya both in space and time. Previous studies focused on regional investigations or the influence of snow melt on the local hydrological system.

Bioengineering Human Tissues and the Future of Vascular Replacement.

Cardiovascular defects, injuries, and degenerative diseases often require surgical intervention and the use of implantable replacement material and conduits. Traditional vascular grafts made of synthetic polymers, animal and cadaveric tissues, or autologous vasculature have been utilized for almost a century with well-characterized outcomes, leaving areas of unmet need for the patients in terms of durability and long-term patency, susceptibility to infection, immunogenicity associated with the risk of rejection, and inflammation and mechanical failure. Research to address these limitations is exploring avenues as diverse as gene therapy, cell therapy, cell reprogramming, and bioengineering of human tissue and replacement organs.