Publications by authors named "K NOVOTNY"

Background: The transition of the United States Medical Licensing Examination Step 1 to a pass/fail scoring system is reshaping its role in medical students' residency placements. This compels institutions to rethink Step 2 preparation strategies, raising concerns about a clerkship's impact on various student groups. Traditionally, medical schools followed the traditional block rotation model for clerkships, which limits longitudinal learning, and many schools are switching to longitudinal integrated clerkships and longitudinal interleaved clerkships (LInCs).

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  • * A dual acoustic-optic laser strategy is introduced, combining laser-induced breakdown spectroscopy (LIBS) and laser-induced plasma acoustics (LIPAc) to create detailed surface images and analyze the mineral composition and physical attributes of rocks embedded in resin.
  • * The combined optical and acoustic data enable better differentiation of mineral phases and provide insights into geological history and polymorphic transformations, demonstrated through the investigation of a septarian nodule with diverse mineral origins.
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  • Laser-induced breakdown spectroscopy (LIBS) enhances immunochemical assays using indirect label detection with nanoparticles, specifically yttrium-based photon-upconversion nanoparticles (UCNPs), achieving sensitivity comparable to established methods like fluorescence immunoassays.
  • The study improves the sensitivity of UCNP-based Tag-LIBS by incorporating magnetic microbeads (MBs), which allow for analyte preconcentration and significantly lowers the limit of detection (LOD) to 4.0 pg/mL, a notable advancement over traditional microtiter plate methods.
  • The technique demonstrates robust performance in clinical samples and shows strong correlation with standard assays, indicating that MB-based Tag-LIBS offers fast readout, high sensitivity, and potential for multiplexing without relying
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People are exposed to microplastics (MPs) on a large scale in everyday life. However, it is not clear whether MPs can also be distributed and retained in certain tissues. Therefore, the development of analytical methods capable of detecting MPs in specific human organs/tissues is of utmost importance.

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Contamination of the environment with toxic metals such as cadmium or lead is a worldwide issue. The accumulator of metals Cannabis sativa L. has potential to be utilized in phytoremediation, which is an environmentally friendly way of soil decontamination.

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