Publications by authors named "K NASU"

Purpose: In image-guided surgery for breast cancer, the representation of the breast deformation between planning and surgery plays a key role. The breast deforms significantly and behaves as a fluid with some constraints. Concretely, the deep fat layer in the breast deforms fluidly due to its incomplete fixation to the chest wall, while the anchoring structures by fascia avoid excessive deformation.

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We report two cases of successful percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) lesion with an anomalous origin of the right coronary artery (AORCA) and challenging guiding catheter engagement using a new 3D virtual reality (VR) guiding catheter simulation system. Appropriate guiding catheter selection is critical for a successful complex PCI. A more suitable guiding catheter size, shape, and position with a robust backup force often leads to the successful completion of more accessible and safer procedures.

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Spontaneous retroperitoneal parasitic leiomyomas are extremely rare and are mostly located in the pelvic cavity. Herein, we present a case of a small primary parasitic leiomyoma arising in the retroperitoneum. A 46-year-old Japanese woman presented with iron deficiency anemia.

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A 50-year-old male with a pancreatic tail tumor underwent distal pancreatectomy. At 14 and 27 months after the primary surgery, metachronous liver metastases were identified and partial hepatectomies were performed for each. Pathologic findings of the primary pancreatic tumor were heterogeneous, but they essentially categorized into two components based on their cytologic features: (i) clear cell component and (ii) epithelioid cell component.

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Article Synopsis
  • HIV-1-infected individuals on antiretroviral therapy still face higher risks of non-AIDS-related health issues due to ongoing chronic inflammation, marked by specific changes in monocytes like increased CD16 subsets and elevated soluble markers sCD163 and sCD14.
  • The study reveals that IL-10, an anti-inflammatory cytokine, can activate monocytes by increasing CD16 and other soluble markers through multiple signaling pathways, including Stat3 and AMPK.
  • Additionally, the HIV-1 protein Nef promotes the production of IL-10 in macrophages, suggesting that IL-10 contributes to the persistent activated state of monocytes in individuals who have achieved viral suppression.
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