Publications by authors named "K N Santhosh"

Article Synopsis
  • * The treatment plan incorporated traditional Ayurvedic concepts and involved using medicines like Varanadi Kashaya and Shilajitvadi Bati, leading to a significant reduction in triglycerides (to 283 mg/dL) and improved urinary symptoms after one month.
  • * Over 1.5 years, the patient continued to show improvement in triglyceride levels and urinary symptoms, demonstrating the potential efficacy of Ayurvedic treatments for patients with obesity and urinary disorders.
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Finding new class of materials to overcome limitation in conventional membranes is a challenging task. Use of naturally stable and sustainable alternative materials stock is an emerging task. In this direction, a novel iron-zirconium hybrid aminoclay (FZ-AC) has emerged as a promising catalyst effectively employed to alleviate fouling concerns within the framework of a biopolymer-based thin film composite (TFC), constructed on a cellulose acetate (CA) support.

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The search for mechanism-based anti-inflammatory therapies is of fundamental importance to avoid undesired off-target effects. Phospholipase A (PLA) activity is a potential molecular target for anti-inflammatory drugs because it fuels arachidonic acid needed to synthesize inflammation mediators, such as prostaglandins. Herein, we aim to investigate the molecular mechanism by which β-keto amyrin isolated from a methanolic extract of Cryptostegia grandiflora R.

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Heavy metal pollution has significant impacts on aquatic fauna and flora. It accumulates in marine organisms, both plants and animals, which are then consumed by humans. This can lead to various health problems, such as organ damage and the development of cancer.

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Objectives: The presentation and outcomes of acute decompensated heart failure (ADHF) during COVID times (June 2020 to Dec 2020) were compared with the historical control during the same period in 2019.

Methods: Data of 4806 consecutive patients of acute HF admitted in 22 centres in the country were collected during this period. The admission patterns, aetiology, outcomes, prescription of guideline-directed medical therapy (GDMT) and interventions were analysed in this retrospective study.

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