Unsupervised methods in LC-MS data treatment: Application for potential chemotaxonomic markers search.

The combination of Liquid Chromatography and Mass Spectrometry (LC-MS) is commonly used to determine and characterize biologically active compounds because of its high resolution and sensitivity. In this work we explore the interpretation of LC-MS data using multivariate statistical analysis algorithms to extract useful chemical information and identify clusters of similar samples. Samples of leaves from 19 plants belonging to the Apiaceae family were analyzed in unified LC conditions by high- and low-resolution mass spectrometry in a wide range scan mode.

A double-blind pilot dosing study of low field magnetic stimulation (LFMS) for treatment-resistant depression (TRD).

Background: Low field magnetic stimulation is a potentially rapid-acting treatment for depression with mood-enhancing effects in as little as one 20-min session. The most convincing data for LFMS has come from treating bipolar depression. We examined whether LFMS also has rapid mood-enhancing effects in treatment-resistant major depressive disorder, and whether these effects are dose-dependent.

Store-and-forward teledermatology for the most common skin neoplasms in Ukraine.

Background: Among all malignancies in Ukraine in 2016, the group of non-melanoma skin cancers headed the list in men and made up 21.6%. This group was second in women and made up 17.

[The automated diagnosis of different forms of ischemic heart disease in the practice of a telecardiology diagnostic center].

The data of the authors' work based on the experience gained with 36,500 telecardiological consultations provided within the framework of the counselling center point to the importance of taking into consideration, in addition to the ECG readings, of the clinical data on the patient to formulate the final diagnosis. In order to obtain formalized clinical information, a coding chart including 19 signs with regard to the gradation in the monotonously increasing extent of derangements has been elaborated. The mathematic maintenance of the work using algorithms of image recognition made it possible to derive a linear formula for computing the magnitude of the total diagnostic index.