[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells].

The radio-sensitizing capacity of cultured HeLa cells was investigated by using a number of compounds, which are analogues of purine and pyrimidine bases. Agents (5-fluorouracil, ftorafur, mercaptopyrine) used in chemotherapy for tumors for many years and some compounds (allopurinol and theophylline) that are sterically close to purine and pyrimidine bases and clinically used for various purposes, but have no cytotoxic activity against tumors cells were tested. Fluorouracil was shown to potentiate the action of gamma-radiation when the agent was given used before radiation or used in the concentrations producing no cytotoxic effect.

[Role of transvesical ultrasonic scanning in the diagnosis of causes of ureteral stenosis in patients with cervical cancer].

gamma-Beam therapy of combined radiation therapy are frequently followed by ureteral obstruction, caused by a cervical cancer recurrence or pelvic postradiation fibrosis. The knowledge of a cause is very important for a choice of therapeutic tactics of obstructive uropathy. The purpose was to define the potentialities of transvesical ultrasound scanning (TVUSS) in order to reveal causes of disturbed urodynamics of the urinary tracts after radiation therapy of cervical cancer.