Publications by authors named "K N Gopalan"
Article Synopsis
- - Dermatophytosis, a type of fungal skin infection, is increasingly common globally, with a study conducted on 3,068 outpatients revealing a prevalence rate of 13.69% among 420 diagnosed cases.
- - The majority of affected patients were female (50.71%) and the most represented age group was 31-40 years, with atypical presentations like tinea incognita being the most frequently observed manifestation.
- - The study found more new cases (326) compared to previously diagnosed ones (94), highlighting that dermatophytic mycoses are a significant concern within this population.
Article Synopsis
- Mutations in ABCA3, a crucial transporter for lung surfactant balance, are the leading genetic cause of childhood interstitial lung disease (chILD), but effective treatments are limited due to a lack of understanding of how these mutations cause disease.
- Researchers generated induced pluripotent stem cells (iPSCs) from affected patients with ABCA3 mutations to create alveolar type II epithelial cells (AEC2s) for in vitro modeling, which revealed decreased surfactant secretion and unexpected abnormal characteristics in mutant cells.
- Using ABCA3:GFP fusion reporters, the study quantified how different ABCA3 mutations affect lamellar body size and protein trafficking, providing insights into the
Background: Nonvenereal dermatoses (NVD) are the spectrum of disorders involving the genitalia with varied etiology and having a considerable influence on the health-related quality of life (QOL), but it remains under evaluated.
Objective: To study the prevalence, pattern, and the effect of nonvenereal genital dermatoses on the QOL of patients with the help of dermatological life quality index (DLQI) questionnaire.
Materials And Methods: This was a cross-sectional study conducted for a period of 1 year.
Background: The incidence of tinea incognita (TI) appears to have increased over recent years owing to the easy availability of topical corticosteroids as over-the-counter preparations.
Aim: Describing the various clinicoepidemiological aspects of TI and assessing the treatment strategies and prescribing practices followed for its management.
Materials And Methods: A prospective study was conducted with 170 patients in the department of Skin and STD of a tertiary care hospital at Salem from Jan 2022 to June 2022.
Background: Androgenetic alopecia (AGA) is a common cause of hair loss in men with limited treatment options. Platelet-rich plasma (PRP) therapy is one of the newer treatment modalities in the management of AGA with promising results.
Aim: The aim is to assess the efficacy of PRP in males with AGA and to study any adverse events associated with the procedure.