Publications by authors named "K Munekage"
Article Synopsis
- Adult colonic intussusceptions are uncommon and often related to organic lead points, but the exact causes and mechanisms remain unclear.
- A case study of a 74-year-old woman showed retrograde colonic intussusception linked to previous colonoscopies, despite no identifiable lead point found during examination.
- This finding is significant as it is the first reported case of colonoscopy-related retrograde intussusception without visible abnormalities, suggesting new avenues for understanding how this condition can occur.
Article Synopsis
- Nonalcoholic fatty liver diseases (NAFLD) and nonalcoholic steatohepatitis (NASH) can lead to hepatocellular carcinoma (HCC), prompting a study of risk stratification methods using histological features and noninvasive markers in patients with liver biopsy-confirmed NAFLD or NASH.
- The study included 1389 patients and compared the predictive ability of histological factors and noninvasive models such as the aMAP score, FIB-4 index, and ALBI score, revealing that the aMAP score had the highest predictive power for HCC.
- The aMAP score and FIB-4 index were found to be superior to histological features for
Article Synopsis
- Researchers found that the Fibrosis-3 (FIB-3) index can accurately predict liver fibrosis progression in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), regardless of age.
- In a study of 1,398 patients, the FIB-3 index performed as well as the Fibrosis-4 (FIB-4) index for those under 60, but outperformed it for patients aged 60 and older.
- The FIB-3 index’s effectiveness suggests it could be a more reliable tool for assessing liver fibrosis than existing methods, enhancing diagnosis across different age groups.
Aims: A multi-stakeholder consensus has proposed MASLD (metabolic dysfunction-associated steatotic liver disease). We aimed to investigate the pathological findings related to the mid-term mortality of patients with biopsy-proven MASLD in Japan.
Methods: We enrolled 1349 patients with biopsy-proven MASLD.
Article Synopsis
- The study redefines nonalcoholic fatty liver disease (NAFLD) as metabolic dysfunction-associated steatotic liver disease (MASLD), analyzing its prognosis through a multicenter study involving 1,398 patients.
- Approximately 99% of the patients were diagnosed with MASLD, showing that those without cardiometabolic risk factors had a significantly lower body mass index (BMI) and less severe liver histology.
- The prognosis for patients with MASLD remained similar to previous findings for NAFLD, with most deaths attributed to extrahepatic cancers and liver-related complications being less common among those without metabolic risks.