Publications by authors named "K Mueck"
Objectives: Some centers have recommended including concentrated fibrinogen replacement in massive transfusion protocols (MTPs). Given our center's policy of aggressive early balanced resuscitation (1:1:1), beginning prehospital, we hypothesized that our rates of hypofibrinogenemia may be lower than those previously reported.
Methods: In this retrospective cohort study, patients presenting to our trauma center November 2017 to April 2021 were reviewed.
Impact of COVID status and blood group on complications in patients in hemorrhagic shock.
Trauma Surg Acute Care Open
March 2024
Objective: Among critically injured patients of various blood groups, we sought to compare survival and complication rates between COVID-19-positive and COVID-19-negative cohorts.
Background: SARS-CoV-2 infections have been shown to cause endothelial injury and dysfunctional coagulation. We hypothesized that, among patients with trauma in hemorrhagic shock, COVID-19-positive status would be associated with increased mortality and inpatient complications.
Patients undergoing trauma laparotomy experience high rates of surgical site infection (SSI). Although intra-operative shock is a likely contributor to SSI risk, little is known about the relation between shock, intra-operative restoration of physiologic normalcy, and SSI development. A retrospective review of trauma patients who underwent emergent definitive laparotomy was performed.
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- This study investigates patient-reported outcomes (PROs) in individuals who experienced abdominal trauma, comparing those who underwent definitive laparotomy (DEF) with those treated with damage control laparotomy (DCL).
- A randomized trial found that both groups had functional limitations after surgery, with survival rates indicating a higher death count in the DEF group and some differences in EQ-5D scores at discharge and six months later.
- The results suggest that functional deficits persist for trauma patients regardless of the type of surgery, highlighting the need for long-term research to guide recovery expectations.
Background: Hemorrhagic shock in the setting of traumatic brain injury (TBI) reduces cerebral blood flow and doubles mortality. The optimal resuscitation strategy for hemorrhage in the setting of TBI is unknown. We hypothesized that, among patients presenting with concomitant hemorrhagic shock and TBI, resuscitation including whole blood (WB) is associated with decreased overall and TBI-related mortality when compared with patients receiving component (COMP) therapy alone.
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