Artificial urinary sphincters (AUS) are an effective treatment for male stress urinary incontinence (SUI). However, infection, erosion, mechanical failure, atrophy, and balloon deterioration cause device malfunction in approximately half of patients by 10 years after implantation. Many patients desire to regain urinary continence and require revision surgery (RS), including device removal and simultaneous or delayed implantation.
View Article and Find Full Text PDF[Purpose] This study aimed to investigate the effects of repetitive peripheral magnetic stimulation of the common fibular nerve on the modification of neural circuit function as measured through the soleus muscle Hoffmann reflex. [Participants and Methods] Twenty-four healthy adult males were randomly and equally divided into the magnetic stimulation (experimental) and control groups. The Hoffmann reflex of the soleus muscle was analyzed before and after 10 min of repetitive peripheral magnetic stimulation for the experimental group and before and after 10 min of rest for the control group.
View Article and Find Full Text PDFTyrosine kinase inhibitors (TKIs) play a crucial role in the treatment of advanced renal cell carcinoma (RCC). However, there is a lack of useful biomarkers for assessing treatment efficacy. Through urinary metabolite analysis, we identified the metabolites and pathways involved in TKI resistance and elucidated the mechanism of TKI resistance.
View Article and Find Full Text PDFAortic and valvular calcification are well-known risk factors for cardio-cerebrovascular events in patients undergoing hemodialysis. We investigated the clinical impact of an angulated aorto-septal angle as a result of aortic elongation due to aortic calcification on cardio-cerebrovascular outcomes in patients undergoing hemodialysis. We investigated 306 patients (mean age 65.
View Article and Find Full Text PDF