Publications by authors named "K Morino"

Omega-3 (ω-3) polyunsaturated fatty acids in fish oil have been shown to prevent diet-induced obesity in lean mice and to promote heat production in adipose tissue. However, the effects of fish oil on obese animals remain unclear. This study investigated the effects of fish oil in obese mice.

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The patient was a 52-year-old male, who, after experiencing lower back pain, underwent further investigation and was diagnosed with hepatocellular carcinoma with sacral metastasis. The hepatocellular carcinoma was a 9 cm tumor with a risk of rupture. Liver resection was performed, and lenvatinib was initiated at a dose of 4 mg/day postoperatively.

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Chylous ascites, a rare but severe complication of abdominal surgery, often results from lymphatic vessel damage during procedures, such as extended resection and lymphadenectomy. Although conservative management through dietary modifications and medications is the primary approach, refractory cases may lead to severe complications including nutritional deficiencies and even death. Herein, we report a case of refractory chylous ascites that progressed to chylothorax after extended right hepatectomy with lymph node dissection for intrahepatic cholangiocarcinoma.

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Article Synopsis
  • Prebiotic synthesis of complex organic molecules has been difficult, but recent observations of liquid CO emissions in deep-sea environments suggest the existence of benthic CO pools.
  • A new hypothesis proposes that a two-phase environment of supercritical CO (ScCO) and water can enhance the dehydration and condensation of organic compounds.
  • Experiments demonstrated that this ScCO-water environment successfully produced various nucleoside monophosphates, indicating its potential to stimulate prebiotic nucleotide synthesis in extreme conditions, relevant both on Earth and in extraterrestrial ocean worlds.
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Article Synopsis
  • The study aims to find genetic factors that contribute to myopic macular neovascularization (mMNV) in people with severe myopia through a genome-wide association study (GWAS) meta-analysis.
  • Researchers analyzed data from 2,783 highly myopic individuals, including 608 with mMNV and 2,175 controls, using advanced genetic analysis techniques.
  • The study discovered a new genetic variant, rs56257842, associated with a lower risk of mMNV, and found that certain transcription factors interacted differently with this variant, suggesting it plays a significant role in the disease's development.
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