Publications by authors named "K Mizumoto"
Visualizing the subcellular localization of presynaptic proteins with fluorescent proteins is a powerful tool to dissect the genetic and molecular mechanisms underlying synapse formation and patterning in live animals. Here, we utilize split green and red fluorescent proteins to visualize the localization of endogenously expressed presynaptic proteins at a single neuron resolution in Caenorhabditis elegans. By using CRISPR/Cas9 genome editing, we generated a collection of C.
View Article and Find Full Text PDFDuring the COVID-19 pandemic, widespread school closures were implemented globally based on the assumption that transmission among children in the school environment is common. However, evidence regarding secondary infection rates by school type and level of contact is lacking. Our study estimated the frequency of SARS-CoV-2 infection in school settings by examining the positivity rate according to school type and level of contact by using data from a large-scale school-based PCR project conducted in Okinawa, Japan, during 2021-2022.
View Article and Find Full Text PDFArticle Synopsis
- Motor circuits are crucial for producing various movements, from simple actions like swimming to complex tasks like human manipulation.
- Research has shown that despite long-standing efforts, understanding of motor circuit development and function is still lacking, but recent advancements provide new tools for exploration.
- Recent studies on both vertebrates (like mice and frogs) and invertebrates (such as nematodes and fruit flies) have revealed important cellular and molecular processes in the development and functioning of motor circuits, highlighting both shared and unique mechanisms across species.
We estimated the seroprevalence of anti-SARS-COV-2 IgG in different island groups in Okinawa. A cross-sectional sero-survey was repeated in three periods between July 2020 and February 2021. A total of 2683 serum samples were collected from six referral medical centers, each covering a separate region in Okinawa.
View Article and Find Full Text PDFObjective: This study aimed to clarify the molecular mechanism of remnant pancreatic cancer (PC) development after primary PC resection.
Summary Background Data: Molecular mechanisms of the development of remnant PCs following primary PC resection are largely unknown.
Methods: Forty-three patients undergoing remnant PC resection after primary PC resection between 2001 and 2017 at 26 institutes were retrospectively analyzed.