Publications by authors named "K Misu"
Introduction: This study aimed to identify when ocular biomarker changes occur within 1 month and which ocular biomarkers correlate with best-corrected visual acuity (BCVA) at months 1 and 6.
Methods: We evaluated 33 patients with Vogt-Koyanagi-Harada disease who received pulse steroid therapy. The central anterior-chamber depth (ACD) and peripheral ACD were evaluated.
Article Synopsis
- The study investigates the link between the p53 signature and ovarian cancer risk in patients with pathogenic variants who underwent risk-reducing salpingo-oophorectomy (RRSO).
- Results indicated that pathogenic variants were significantly more prevalent in the RRSO group compared to controls, but there was no significant difference in the frequency of p53 signatures between the two groups.
- The analysis identified two types of p53 signatures, one associated with a higher risk of progression to serious conditions like serous tubal intraepithelial carcinoma (STIC) and cancer, and another linked to a lower risk seen in control patients without pathogenic variants.
Background: Pleuroperitoneal communication is a rare disorder that interferes with peritoneal dialysis. Although favorable results of thoracoscopic fistula closure have been reported, there are some cases in which the fistulas cannot be identified by thoracoscopy and the patients are forced to switch to hemodialysis.
Case Presentation: We present two cases of pleuroperitoneal communication in which diaphragmatic fistulas could not be identified thoracoscopically, but could be identified laparoscopically.
Hereditary leiomyomatosis and renal cell carcinoma (HL (RCC)) entails cutaneous and uterine leiomyomatosis with aggressive type 2 papillary RCC-like histology. HLRCC is caused by pathogenic variants in the FH gene, which encodes fumarate hydratase (FH). Here, we describe an episode of young-onset RCC caused by a genomic FH deletion that was diagnosed via clinical sequencing.
View Article and Find Full Text PDFBackground: Risk-reducing salpingo-oophorectomy is performed for the primary prevention of ovarian cancer in patients with hereditary breast-ovarian cancer syndrome. We performed risk-reducing salpingo-oophorectomy for the first time in Japan in 2008, and we experienced 20 cases of risk-reducing salpingo-oophorectomy through 2019. In the past, the use of risk-reducing salpingo-oophorectomy in Japan was restricted because it was not covered by a Japanese National Health Insurance.
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