Publications by authors named "K Mima"
Article Synopsis
- - The study examined the effect of aspirin on patients with hepatocellular carcinoma (HCC) who had liver surgery, finding that those who took aspirin showed improved outcomes compared to those who didn't.
- - Out of 1,032 patients, 87 were in the aspirin group, and results indicated significantly higher five-year recurrence-free survival (RFS) and overall survival (OS) rates for these patients.
- - The conclusion suggested that aspirin use may lead to better prognosis for HCC patients post-liver resection, highlighting the potential benefits of aspirin in this context.
Purpose: It has reported that the prevalence of frailty in patients with pancreatic cancer is 45%. The number of patients with pancreatic cancer is increasing, and within this cohort, patients often suffer from impaired activities of daily living (ADLs). This study aimed to examine the association between perioperative Barthel Index (BI) scores, a validated measure of ADLs, and survival outcomes after pancreatectomy for pancreatic cancer.
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- The study aims to assess the effectiveness and impact of minimally invasive pancreatoduodenectomy (MIPD) compared to open pancreatoduodenectomy (OPD) on patients' nutrition and immune response post-surgery.
- Out of 306 patients analyzed, MIPD showed significant benefits over OPD, including less blood loss, fewer transfusions, shorter hospital stays, and fewer complications, though it had a longer operation time.
- Despite these surgical advantages, nutritional and immunological outcomes, such as albumin levels and other indices, were similar between the two surgical methods.
Background & Aims: Epidemiologic evidence for dietary influence on colorectal cancer (CRC) risk through the gut microbiome remains limited.
Methods: Leveraging 307 men and 212 women with stool metagenomes and dietary data, we characterized and validated a sex-specific dietary pattern associated with the CRC-related gut microbial signature (CRC Microbial Dietary Score [CMDS]). We evaluated the associations of CMDS with CRC risk according to Fusobacterium nucleatum, pksEscherichia coli, and enterotoxigenic Bacteroides fragilis status in tumor tissue using Cox proportional hazards regression in the Health Professionals Follow-Up Study (1986-2018), Nurses' Health Study (1984-2020), and Nurses' Health Study II (1991-2019).
Evidence indicates that combinations of anti-EGFR antibodies and KRAS p.G12C (c.34G>T) inhibitors can be an effective treatment strategy for advanced colorectal cancer.
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