Publications by authors named "K Michelle Rosado"
Article Synopsis
- - Gastric cancer is a leading cause of cancer deaths globally, often linked to chronic infection by a common bacterium, which can lead to gastric intestinal metaplasia (GIM), a key pre-cancerous condition.
- - A study analyzed pathology data from nearly 44,000 endoscopy biopsies in Puerto Rico from 2012-2014 and found a GIM prevalence rate of 10.7%, with a significant portion of reports lacking critical risk subtype information.
- - The findings suggest higher GIM prevalence among Puerto Rican Hispanics compared to non-Hispanic populations in the U.S., highlighting the need for improved standardization in biopsy protocols and pathology reporting to enhance GIM surveillance.
Implementation of Universal Colorectal Cancer Screening for Lynch Syndrome in Hispanics Living in Puerto Rico.
J Racial Ethn Health Disparities
October 2021
Objective: Colorectal cancer is the leading cause of cancer death in Puerto Rico and third among Hispanics in the USA. Up to 2-4% of colorectal cancer cases are a result of Lynch syndrome (LS), a hereditary cancer syndrome caused by a germline mutation in at least one of the DNA mismatch repair genes. The objective of this study was to determine the prevalence of LS in colorectal tumors during the first 15-months after the implementation of universal tumor-based screening for LS in Puerto Rico.
View Article and Find Full Text PDFIntroduction: The purpose of this study was to determine the impact of an in-home expiratory muscle strength training (EMST) program on pulmonary, swallow, and cough function in individuals with amyotrophic lateral sclerosis (ALS).
Methods: EMST was tested in a prospective, single-center, double-blind, randomized, controlled trial of 48 ALS individuals who completed 8 weeks of either active EMST (n = 24) or sham EMST (n = 24). The primary outcome to assess treatment efficacy was change in maximum expiratory pressure (MEP).
Respiratory training in an individual with amyotrophic lateral sclerosis.
Ann Clin Transl Neurol
October 2016
We examined the impact of expiratory muscle strength training on maximum expiratory pressure, cough spirometry, and disease progression in a 71-year-old male with amyotrophic lateral sclerosis. Maximum expiratory pressure declined 9% over an 8-week sham training period, but subsequently improved by 102% following 8 weeks of expiratory muscle strength training. Improvements in cough spirometry and mitigated disease progression were also observed post expiratory muscle strength training.
View Article and Find Full Text PDFObjective: The aim of this study was to determine the prevalence of NASH in veterans with metabolic syndrome and compare histologic grading using the Brunt criteria, the NAFLD activity score (NAS), and a proposed NAS scoring system that has been modified to include fibrosis staging.
Methods: Veterans with metabolic syndrome, hepatic steatosis, and elevated ALT and AST levels and who underwent liver biopsies from 2004 through 2010 were included in this study. Biopsies were evaluated by a single hepatopathologist.