A scoping review on pediatric sepsis prediction technologies in healthcare.

This scoping review evaluates recent advancements in data-driven technologies for predicting non-neonatal pediatric sepsis, including artificial intelligence, machine learning, and other methodologies. Of the 27 included studies, 23 (85%) were single-center investigations, and 16 (59%) used logistic regression. Notably, 20 (74%) studies used datasets with a low prevalence of sepsis-related outcomes, with area under the receiver operating characteristic scores ranging from 0.

How was That for You?: Gender, Aftercare and Impression Management in BDSM.

Existing research finds that people's perspectives on sexual interactions shift with time and new experiences. Despite this, little empirical work has explored the role that communication following a sexual interaction plays in partners' perceptions of each other and the sexual interaction. This study began to address this gap by applying impression management theory and gender performance theory to analyze 40 interviews with BDSM (Bondage/discipline, Dominance/submission, Sadism, Masochism) practitioners who "top," or enact a dominant role, about a community-held practice called "aftercare.

Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues.

Microbe-produced molecules (xenometabolites) found in foods or produced by gut microbiota are increasingly implicated in microbe-microbe and microbe-host communication. Xenolipids, in particular, are a class of metabolites for which the full catalog remains to be elaborated in mammalian systems. We and others have observed that cis-3,4-methylene-heptanoylcarnitine is a lipid derivative that is one of the most abundant medium-chain acylcarnitines in human blood, hypothesized to be a product of incomplete β-oxidation of one or more "odd-chain" long-chain cyclopropane fatty acids (CpFAs).

CDC's Laboratory Activities to Support Newborn Screening for Spinal Muscular Atrophy.

Spinal muscular atrophy (SMA) was added to the HHS Secretary's Recommended Uniform Screening Panel for newborn screening (NBS) in 2018, enabling early diagnosis and treatment of impacted infants to prevent irreversible motor neuron damage. In anticipation of supporting SMA newborn screening, scientists at the U.S.

A national survey of medication utilization for cardiac resuscitation in the emergency department: A survey of emergency medicine pharmacists.

Purpose: Vasoactive medications are used during advanced cardiac life support (ACLS) to shunt oxygenated blood to vital organs and after return of spontaneous circulation (ROSC) to maintain hemodynamic goals. However, limited evidence exists to support vasoactive medication recommendations in such scenarios, and it is unknown how practices vary among emergency departments across the US.

Methods: A survey questionnaire (15 questions) was electronically distributed to emergency medicine pharmacists (EMPs) in the US through various professional listservs.