Publications by authors named "K Mazur-Melewska"
Background: Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022.
Objectives: This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections.
Article Synopsis
- Lyme borreliosis (LB) is a significant health issue, causing numerous infections in children, and this study is the first to link it with environmental factors.
- Researchers analyzed medical records of 196 children diagnosed with LB in Poland and found a positive correlation between LB cases and environmental elements like deer density, broadleaved forest coverage, and urbanization.
- Results indicated that LB cases in children increased with urbanization and forest coverage, particularly in males, with a notable rise in cases from 2017 to 2021, highlighting the relationship between deer density and infection risk.
This study investigates the impact of Epstein-Barr virus (EBV) infection on children's proteomes across different phases of the disease, utilising seventy-nine blood samples categorised into three groups: EBV-naive patients, acute infectious mononucleosis (IM) cases, and convalescents followed up for 12 months post-IM. The aim is to identify proteins influenced by EBV infection, shedding light on the chronic processes triggered by the virus. The results reveal thirty-nine proteins distinguishing between naive patients and those with IM, including actin, lumican, peroxiredoxin-2, fibulin-1, gelsolin, and alpha-2-macroglobulin, which are involved in immune responses, cell adhesion, and inflammation.
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- The Poxviridae family consists of a variety of viruses, divided into two subfamilies: Chordopoxvirinae for vertebrates and Entomopoxvirinae for insects, with only three species that can infect humans.
- Post-smallpox eradication in 1980, mass vaccination was stopped, leaving many, especially children, unprotected against Orthopoxvirus (OPV).
- This chapter aims to explore the causes, symptoms, diagnosis, and treatment of Poxviridae infections in pediatric populations.
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by several core symptoms: restricted interests, communication difficulties, and impaired social interactions. Many ASD children experience gastrointestinal functional disorders, impacting their well-being. Emerging evidence suggests that a gut microbiota imbalance may exacerbate core and gastrointestinal symptoms.
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