Publications by authors named "K Mazaz"

Article Synopsis
  • The study explored how molecular changes in patients with stage I-IV colorectal cancer (CRC) affect the timing and location of cancer recurrence, aiming to identify factors that influence recurrence-free survival.
  • Out of 270 analyzed patients, 31% had recurrence, with significant correlations found between early recurrence and factors like age, tumor differentiation, and specific mutations, notably in the RAS gene.
  • The findings suggest that the molecular profile of patients, particularly mutations in codon 12, can serve as a strong predictor of recurrence-free survival across all cancer stages.
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Introduction And Importance: Inflammatory myofibroblastic tumors constitute a group of mesenchymal tumors associated with inflammatory infiltration. They occur mainly in young patients. It is classified by the World Health Organization as a borderline neoplasm.

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In patients with locally advanced rectal cancer, neoadjuvant radiotherapy or chemoradiotherapy followed by total mesorectal excision as a standard of care. We aimed to explore the number, size, germinal centers, extracapsular invasion of lymph nodes (LN), and their impact on overall survival and disease free survival. Furthermore we also investigated the characteristics of lymph nodes in patients who received neoadjuvant therapy and those who underwent surgery between 2011 and 2018.

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