Mod Rheumatol
May 2017
Rapidly progressive interstitial lung disease (RP-ILD) in patients with clinically amyopathic dermatomyositis (CADM) associated with antibodies to melanoma differentiation-associated gene5 (MDA5) results in a high mortality rate. We experienced a case of anti-MDA5-positive RP-ILD of CADM which showed a response to rituximab, although there was no significant effect due to standard immunosuppressive treatment. This case suggests that rituximab has the potential to offer an effective agent for the treatment of anti-MDA5-positive RP-ILD of CADM.
View Article and Find Full Text PDFMultislice spiral computed tomography (MSCT) is a new non-invasive imaging technique for detecting coronary artery disease. It allows direct visualization of not only the lumen of the coronary arteries, but also plaque within the artery. Identification of soft plaques is of the utmost importance in the therapeutic decision making for patients with acute coronary syndrome (ACS), including acute myocardial infarction and unstable angina pectoris.
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