Publications by authors named "K Masahiko"

Article Synopsis
  • * In a study of 88 Japanese T2DM patients, HbA1c levels decreased by an average of 1.24% and body weight reduced by 1.44 kg after 6 months of oral semaglutide treatment.
  • * The treatment led to a significant increase in the percentage of patients achieving HbA1c levels below 7%, improving various cardiometabolic parameters regardless of factors like age and kidney
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Article Synopsis
  • OW semaglutide, a once-weekly GLP-1 receptor agonist, was found to lower glycated hemoglobin (HbA1c) more effectively than other oral diabetes medications in Japanese patients with type 2 diabetes in a real-world setting.
  • * The study tracked 77 patients over 6 months, showing an average HbA1c decrease of 0.89% and an increase in patients achieving HbA1c levels below 7% from 21% to 43%.
  • *Factors such as higher baseline HbA1c and shorter duration of diabetes predicted better responses, and the treatment was mostly well tolerated among the participants.*
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Rapidly progressive interstitial lung disease (RP-ILD) in patients with clinically amyopathic dermatomyositis (CADM) associated with antibodies to melanoma differentiation-associated gene5 (MDA5) results in a high mortality rate. We experienced a case of anti-MDA5-positive RP-ILD of CADM which showed a response to rituximab, although there was no significant effect due to standard immunosuppressive treatment. This case suggests that rituximab has the potential to offer an effective agent for the treatment of anti-MDA5-positive RP-ILD of CADM.

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Multislice spiral computed tomography (MSCT) is a new non-invasive imaging technique for detecting coronary artery disease. It allows direct visualization of not only the lumen of the coronary arteries, but also plaque within the artery. Identification of soft plaques is of the utmost importance in the therapeutic decision making for patients with acute coronary syndrome (ACS), including acute myocardial infarction and unstable angina pectoris.

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