Safety and efficacy of outpatient intravenous diuresis in decompensated heart failure: a systematic review.

Introduction: Heart failure (HF) burdens the US healthcare system, with annual costs exceeding $30 billion. Outpatient intravenous (OP IV) diuresis in clinic or home settings may potentially improve outcomes and reduce costs, though limited data exists. This systematic review evaluates the safety, efficacy, and outcomes of OP IV diuresis in managing decompensated HF as a hospitalization alternative.

Fluid Dynamic and in Vitro Blood Study to Understand Catheter-Related Thrombosis.

Purpose: Central venous catheters (CVCs) provide a direct route to the venous circulation but are prone to catheter-related thrombosis (CRT). A known CRT risk factor is a high catheter-to-vein ratio (CVR), or a large catheter diameter with respect to the indwelling vein size. In this study, the CVR's effect on CVC hemodynamics and its impact on CRT is investigated with in vitro and in silico experiments.

Clinical and Histopathological Findings in HIV-positive to HIV-positive Kidney Transplant Recipients.

Background: The spectrum of histological findings in transplanted kidneys from HIV-positive donors to HIV-positive recipients is relatively unexplored. This study describes the type and timing of histological diagnoses observed in this unique cohort.

Methods: Adequate biopsies were analyzed at implantation and posttransplant between September 2008 and May 2022.

GPVI-mediated thrombus stabilization of shear-induced platelet aggregates in a microfluidic stenosis.

Supraphysiological shear rates (>2000 s) amplify von Willebrand factor unfurling and increase platelet activation and adhesion. These elevated shear rates and shear rate gradients also play a role in shear-induced platelet aggregation (SIPA). The primary objective of this study is to investigate the contributions of major binding receptors to platelet deposition and SIPA in a stenotic model.