Publications by authors named "K Makrilakis"
Background: The long-term effects of breakfast on childhood z-BMI remain inconclusive.
Objective: To prospectively assess the impact of stable and altered breakfast consumption habits on z-BMI change over two years, in school-aged children across six European countries.
Methods: Data of 6,528 children (8.
Common mistakes concerning diabetes management in daily clinical practice.
Prim Care Diabetes
December 2024
Diabetes mellitus is a chronic metabolic disease, potentially leading to dire complications. Although there are numerous pharmaceutical treatments available, management of the disease is frequently not optimal. Managing diabetes in daily clinical practice can be challenging, and several common mistakes may occur.
View Article and Find Full Text PDFThe gut microbiota represents a complex ecosystem of trillions of microorganisms residing in the human gastrointestinal tract, which is known to interact with the host physiology and regulate multiple functions. Alterations in gut microbial composition, diversity, and function are referred to as dysbiosis. Dysbiosis has been associated with a variety of chronic diseases, including infections, but also cardiometabolic diseases, including obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDFAim: To examine physical activity levels in association with metabolic health and estimate the stability of metabolically healthy obese (MHO) phenotypes over a 2-year period.
Methods: In total, 2848 men and women from families at risk of the development of diabetes were recruited. Participants were classified as obese or non-obese and metabolic health was defined using five existing definitions.
Article Synopsis
- Community- and school-based lifestyle interventions are effective in preventing type 2 diabetes but many participants drop out of follow-ups, prompting an investigation into what influences ongoing participation in a European study.
- The study analyzed the impact of socioeconomic, sociodemographic, and clinical factors on 2,702 participants from six different countries, identifying significant differences related to gender, education, employment, BMI, and blood pressure.
- Findings indicated that higher education and employment levels were linked to lower drop-out rates, particularly in high-income countries, while female participants in low-to-middle-income countries showed better retention; overall, demographics and BMI were crucial for understanding participant engagement in these programs.